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There are conflicting data, i.e., some models show GABAergic excess as opposed to deficiency data, which illustrates the heterogeneity of ASD
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In melanoDerm skin model, arbutin showed only marginal efficacy on melanin production with an IC 50 value of 500 μmol/L, while kojic acid inhibited with an IC 50 of 400 μmol/L
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