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BSO-mediated activation of NF-kappaB leads to multiple cell-protective responses, such as the trans-activation of heat shock protein 27, which stops the apoptotic signal after Bax translocation and cytochrome c release (Filomeni et al., 2005), and the main anti-apoptotic protein Bcl-2
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Numbness and Tingling : These sensations can occur in the areas served by the affected nerves
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