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The antioxidant N-acetylcysteine promotes atherosclerotic plaque stabilization through suppression of RAGE, MMPs and NF-kappaB in ApoE-deficient mice

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I won't go into the arachidonic acid pathway except to note that arachidonic acid, a critically important biomolecule, can be processed in either of two ways, depending on the enzymes that modify it Arachidonic acid is converted into leukotrienes by an enzyme called lipoxygenase and by another enzyme, cyclooxygenase (COX), into prostaglandins (1) , a large family of potent hormones responsible for a wide variety of physiological responses, including pain and inflammation