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Cellular Senescence as a Targetable Risk Factor for Cardiovascular Diseases: Therapeutic Implications: JACC Family Series | JACC: Basic to Translational Science
Key distinctions between these two pathways include the need for molecular oxygen to aid in ring contraction and cobalt insertion: in the aerobic pathway, this occurs only after the synthesis of hydrogenobyrinic acid a , c ‐diamide (late stage), whereas in the anaerobic pathway (as shown in Figure 3), it occurs at the precorrin‐2 stage (early insertion)
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[DOI] [PMC free article] [PubMed] [Google Scholar] 163.Pasello M., Michelacci F., Scionti I., Hattinger C.M., Zuntini M., Caccuri A.M., Scotlandi K., Picci P., Serra M
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