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Together, our observations that a small molecule NNMT inhibitor can increase NAD + and SAM concentrations in differentiated adipocytes and reduce adiposity in DIO mice, suggest that treatment with an NNMT inhibitor effectively reverses obesity via modulation of the NAD + salvage and SAM-mediated (e.g., polyamine flux) pathways to regulate energy expenditure in the adipose tissue
2-bottles
Size:10 mL (1000 mcg / mL)
[DOI] [PubMed] [Google Scholar] 95.Lee E.J., Kim M.W., Gil H.-N., Chung Y.J., Kim E.M
Ships within 48 hours Β· Estimated delivery Oct 11 - Oct 16
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