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In Parkinson’s disease, the solute carrier transporter of long neutral amino acids SLC7A5 is exploited to transport the precursor of dopamine (levodopa) to restore the levels of this neurotransmitter in the brain parenchyma (Rust et al., 2025)
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Systemic effects include transient fatigue reported in 18% of research subjects within 4-6 hours of administration, typically resolving within 12 hours without intervention
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