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However, utilizing solubilization buffers with a range of pH and ionic strength (0.01–1 M NaCl concentration) as well as detergents such as 1–5% of Triton X-100 and 10 mM CHAPS, IB proteins are recovered up to low to a decent amount of yield (5–20%) [22]
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Metabolic outcomes are similarly mixed but trend favorably when deficiency is corrected, and IR is pronounced
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