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6.4 Other regulatory factors and pathways In the process of SCI, in addition to the classical ERS signaling pathways, an increasing number of studies focus on the effects of other regulatory factors and signaling pathways on ERS and cell fate, especially the regulatory role of the Sigma-1 receptor and the interactions between oxidative stress and inflammatory signals with ERS (Hayashi, 2019)

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coli FdhF gene) in the 3′ untranslated region (3’ UTR), which directs Sec-insertion at the UGA551 codon in recombinantly produced human TrxR1 variants from E