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Key discoveries include the role of airway epithelium-derived cytokines (i.e., “alarmins”) in orchestrating type 2 immunity, 17 the identification of genetic loci conferring asthma susceptibility, and the delineation of distinct inflammatory endotypes (T2-high vs T2-low)
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Nucleocapsid protein of SARS-CoV activates interleukin-6 expression through cellular transcription factor NF-kappaB
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