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In other studies, it was found that GPx1 can also mitigate activation of the ROS-induced apoptosis signal-regulating kinase 1 (ASK1)/JNK-mediated apoptosis [145]
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Others have shown that C3H/HeN mice treated with a combination of ethanol, aloe emodin, and UV radiation develop high numbers of primary cutaneous melanomas, though they didn’t do a comparison with the standard B6 mouse strain (132)
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