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Excessive production of RAGE on brain microvascular endothelial cells increases Aβ transport into the brain tissue and decreases its removal, leading to the accumulation of Aβ in the brain tissue, which in turn triggers a series of neurodegenerative pathological changes, such as the formation of amyloid plaques, the formation of neurofibrillary tangles, and the loss of neurons (23)

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She is the Managing Director of Varanasi & Company, a consulting firm providing medical affairs and strategic consulting for consumer health brands including supplements, health foods, healthtech platforms, aesthetic startups, and media ventures