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For context, two peptides in active, much larger human trial programs today: Retatrutide , a triple GIP/GLP-1/glucagon receptor agonist, produced a mean weight change of -24.2 percent at the highest dose tested versus -2.1 percent on placebo in a 48-week Phase 2 trial, with 83 percent of that highest-dose group losing at least 15 percent of body weight versus 2 percent on placebo (Jastreboff et al., NEJM 2023, PMID 37366315)
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Frequent monitoring of B12 levels is also very important for patients experiencing B12 deficiency
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Check whether a remaining issue needs to stay in the same case. Close the request when the documented issue has been suitably addressed.
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