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Finally, the gut microbiome may contribute to NAFLD pathogenesis: an increased intestinal permeability could lead to the entry of endotoxins in portal circulation and activation, through toll-like receptor 4, of Kupffer cells, with consequent inflammation (50–53)
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Pterostilbene is a methoxylated derivative of resveratrol that showed antibacterial activity against drug-resistant Staphylococcus aureus (MRSA) with minimum inhibitory concentration (MIC) superior of pterostilbene compared to resveratrol (8~16-fold)
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