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In addition, they can also assist in the prevention and treatment of thyroid immune diseases by activating natural killer (NK) cells ( Scrophularia Radix ceae polysaccharides also have antifatigue effects and can improve the symptoms of fatigue and weakness caused by metabolic disorders in patients with thyroid diseases and diabetes ( 2.1.7 Flavonoids Flavonoids are widely present in nature and have various biological activities, such as liver protection, antitumor, and antioxidant effects ( 2.1.8 Alkaloids Alkaloids in Scrophulariae Radix , such as genipin, act mainly on the nervous system and have sedative, antidepressant and antianxiety effects ( 2.1.9 Phenols Phenolic compounds such as chlorogenic acid have antioxidant, anti-inflammatory, and antibacterial effects ( 3 Pharmacological effects Studies on Scrophulariae Radix have highlighted its anti-inflammatory, antioxidant, immunomodulatory, cardiovascular protective, and antitumor effects ( 3.1 Anti-inflammatory effects Key components of Scrophulariae Radix , including iridoid glycosides such as aucubin and geniposide, show strong anti-inflammatory activity (84)

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The comparison describes concentrations in one cell-culture morphology assay and says nothing about maximum effect, duration, or activity in an intact organism