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Supporting the existence of an additional cyclin D-Rb docking interaction, truncation of the Rb C terminus disrupts phosphorylation by cyclin D1-Cdk4 in vitro, and this truncated Rb variant slows division and inhibits E2F-dependent gene expression in cultured cells (Gorges et al., 2008
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α-KG was first applied directly to the treatment of osteoporosis by Yuan’s group in 2020 (116)
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