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Diet-induced obesity models — animal-model research has explored AOD-9604's effect on body composition, fat-mass markers, and energy expenditure in rodent obesity models
Vitamin B12 for Injection
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Trials conducted between 2001 and 2007 demonstrated statistically significant reductions in body fat, although the larger Phase IIb OPTIONS trial did not replicate these findings at sufficient magnitude for regulatory approval, and formal development was discontinued in 2007
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