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Importantly, circulating cell-free DNA (cfDNA) profiling that incorporates fragment size distribution, specifically the presence of 54–149 bp and 209–297 bp fragments alongside absolute concentration and the intracellular-to-extracellular mtDNA copy number ratio, provides substantially greater discriminative power than concentration alone, stratifying patients according to renal functional trajectory and risk of progressive lupus nephritis (117)

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Evitare l’esposizione a fonti di calore, alla luce solare diretta ed ambienti umidi